HMOs Cell Factory — Conference Notes
Human milk oligosaccharides (HMOs) are a class of structurally diverse complex carbohydrates that serve as prebiotics, anti-adhesive antimicrobials, and immunomodulators in infant nutrition. Industrial production of HMOs via microbial fermentation has attracted significant interest, yet several bottlenecks remain: low substrate specificity of glycosyltransferases, difficult co-regulation of precursor synthesis pathways, and unclear key regulatory targets. This post summarizes conference notes from LiuLong (JiangNan University) on a series of strategies addressing these challenges through an integrated synthetic biology workflow.
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